Evaluation of a flexible collagen surgical patch for reinforcement of a fascial defect: Experimental study in a sheep model.

There is a need for a surgical mesh that can be used in general surgical procedures for reinforcement or repair of soft tissue. Collagen based surgical meshes may possess the appropriate qualities. In this study, the potential of a collagen product BioBlanket Surgical Mesh to facilitate soft tissue repair in an ovine fascial defect model in vivo was evaluated. BioBlanket Surgical Mesh facilitated soft tissue repair in an ovine fascial defect model in vivo. Superficial fascial surgical sites were evaluated grossly, histologically, and mechanically at 6 and 12 week time points. BioBlanket Surgical Mesh and the predicate device Restore Orthobiologic Implant both performed favorably when implanted in superficial fascial defects compared with the negative control empty defect.